New platinum (II) complexes with thiophene-2-carbaldehyde thiosemicarbazone derivatives and their antibacterial and antitumor activities

Project: Research

Project Details

Description

It has been shown that some thioemicarbazone derivatives of thiophene and their metal complexes inhibit the growth of various types of bacteria and tumors, due to the rupture of the cell membrane or intercalation within the DNA. In the line of work developed by researchers for some years, this specific project proposes the preparation and biological evaluation of platinum (II) complexes with thioene-2-carbaldehyde thiosemicarbazone derivatives. The compounds will be characterized by masses, infrared and nuclear magnetic resonance (1H, 13C), while biological tests will be performed against different types of bacteria and tumor cell lines of the human being.
StatusFinished
Effective start/end date1/04/1931/03/20