Research output per year
Research output per year
Project Details
Description
It has been shown that some thioemicarbazone derivatives of thiophene and their metal complexes inhibit the growth of various types of bacteria and tumors, due to the rupture of the cell membrane or intercalation within the DNA. In the line of work developed by researchers for some years, this specific project proposes the preparation and biological evaluation of platinum (II) complexes with thioene-2-carbaldehyde thiosemicarbazone derivatives. The compounds will be characterized by masses, infrared and nuclear magnetic resonance (1H, 13C), while biological tests will be performed against different types of bacteria and tumor cell lines of the human being.
| Status | Finished |
|---|---|
| Effective start/end date | 1/04/19 → 31/03/20 |
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Research output
- 1 Article (Contribution to Journal)
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Novel Thiosemicarbazone Derivatives from Furan-2-Carbaldehyde: Synthesis, Characterization, Crystal Structures, and Antibacterial, Antifungal, Antioxidant, and Antitumor Activities
Hernández Gorritti, W. R., Carrasco Solis, F. C., Vaisberg, A., Spodine, E., Icker, M., Krautscheid, H., Beyer, L., Tamariz-Angeles, C. & Olivera-Gonzales, P., 14 Sep 2023, In: journal of chemistry. 2023, ID 5413236, 20 p., Article ID 5413236.Research output: Contribution to journal › Article (Contribution to Journal) › peer-review
Open Access21 Scopus citations
Projects
- 1 Finished
-
QMI: New complexes of platinum (II) and palladium (II) with derivatives of furan-2-carbaldehyde thiosemicarbazone and their antitumor activity
Hernández Gorritti, W. R. (PI), Carrasco Solis, F. C. (CoI), Vaisberg, A. J. (CoI), Spodine, E. (CoI), Icker, M. (CoI), Krautscheid, H. (CoI) & Beyer, L. (CoI)
1/04/21 → 31/03/22
Project: Research