Aim: This paper examines the barriers in Peruvian community pharmacies for cosmetovigilance practice. Methods: It was obtained information from the pharmacists of 81 community pharmacies in 2 districts in Lima, Peru. For reliability's evaluation, it was used SPSS software V.24. The validity of construct, discriminant validity and, internal consistency by the composite reliability was analyzed with structural equation modelling using partial least square using SmartPLS 3 software. Results: 81 questionnaires self-administered anonymous were completed (response rate = 51.9%). Average of years of working in community pharmacies was more than 6.36 years (SD:4.63). More than 70% of the participating pharmacists chose the `'strongly agree'' and `'agree'' alternative for items about barriers that included: Lack of time, National health system structure in general and My interest to report adverse reaction by cosmetics. About daily activities, more than 70% of the participants chose the `'strongly agree'' and `'agree'' alternative for items that included `'Rarely I explain to users about adverse reaction with cosmetics use'' and `'Rarely I have material to inform to users about adverse reaction with cosmetics use''. The composite reliability for each latent variable was Resources: 0,766; Interest: 0862; Regulation: 0.815 and Cosmetovigilance Practice: 0.909. Conclusion: The need of the implementation of cosmetovigilance practice is an issue of public health to take responsibility for care customers against cosmetic damage.