Abstract
Objectives: To determine the probability of controlling the outbreak of COVID-19 in Peru, in a pre- and post-quarantine scenario using mathematical simulation models. Materials and methods: Outbreak simulations for the COVID 19 pandemic are performed, using stochastic equations under the following
assumptions: a pre-quarantine population R0 of 2.7 or 3.5, a post-quarantine R0 of 1.5, 2 or 2.7, 18% or 40%, of asymptomatic positives and a maximum response capacity of 50 or 150 patients in the intensive care units. The success of isolation and contact tracing is evaluated, no other mitigation measures are
included. Results: In the pre-quarantine stage, success in controlling more than 80% of the simulations occurred only if the isolation of positive cases was implemented from the first case, after which there was less than 40% probability of success. In post-quarantine, with 60 positive cases it is necessary to isolate them early, track all of their contacts and decrease the R0 to 1.5 for outbreak control to be successful in more than 80% of cases. Other scenarios have a low probability of success. Conclusions: The control of the outbreak in Peru during pre-quarantine stage demanded requirements that were difficult to comply
with, therefore quarantine was necessary; to successfully suspend it would require a significant reduction in the spread of the disease, early isolation of positives and follow-up of all contacts of positive patients.
assumptions: a pre-quarantine population R0 of 2.7 or 3.5, a post-quarantine R0 of 1.5, 2 or 2.7, 18% or 40%, of asymptomatic positives and a maximum response capacity of 50 or 150 patients in the intensive care units. The success of isolation and contact tracing is evaluated, no other mitigation measures are
included. Results: In the pre-quarantine stage, success in controlling more than 80% of the simulations occurred only if the isolation of positive cases was implemented from the first case, after which there was less than 40% probability of success. In post-quarantine, with 60 positive cases it is necessary to isolate them early, track all of their contacts and decrease the R0 to 1.5 for outbreak control to be successful in more than 80% of cases. Other scenarios have a low probability of success. Conclusions: The control of the outbreak in Peru during pre-quarantine stage demanded requirements that were difficult to comply
with, therefore quarantine was necessary; to successfully suspend it would require a significant reduction in the spread of the disease, early isolation of positives and follow-up of all contacts of positive patients.
Translated title of the contribution | Estimated conditions to control the COVID-19 pandemic in pre- and postquarantine scenarios in Peru |
---|---|
Original language | Undefined/Unknown |
Pages (from-to) | 195 - 202 |
Journal | Revista Peruana de Medicina de Experimental y Salud Publica |
Volume | 37 |
DOIs | |
State | Published - 28 Apr 2020 |
Externally published | Yes |
Keywords
- Coronavirus Infection
- Outbreaks
- Surveillance
- Decision Modelling