TY - JOUR
T1 - Estimated conditions to control the COVID-19 pandemic in pre- and postquarantine scenarios in Peru,Condiciones estimadas para controlar la pandemia de COVID-19 en escenarios de pre y poscuarentena en el Perú
T2 - Condiciones estimadas para controlar la pandemia de COVID-19 en escenarios de pre y poscuarentena en el Perú.
AU - Huamaní, C.
AU - Timaná-Ruiz, R.
AU - Pinedo, J.
AU - Pérez, J.
AU - Vásquez Serpa, Luis Javier
PY - 2020
Y1 - 2020
N2 - Objectives: To determine the probability of controlling the outbreak of COVID-19 in Peru, in a pre- and post-quarantine scenario using mathematical simulation models. Materials and methods: Outbreak simulations for the COVID-19 pandemic are performed, using stochastic equations under the following assumptions: a pre-quarantine population R0 of 2.7 or 3.5, a post-quarantine R0 of 1.5, 2 or 2.7, 18% or 40%, of asymptomatic positives and a maximum response capacity of 50 or 150 patients in the intensive care units. The success of isolation and contact tracing is evaluated, no other mitigation measures are included. Results: In the pre-quarantine stage, success in controlling more than 80% of the simulations occurred only if the isolation of positive cases was implemented from the first case, after which there was less than 40% probability of success. In post-quarantine, with 60 positive cases it is necessary to isolate them early, track all of their contacts and decrease the R0 to 1.5 for outbreak control to be successful in more than 80% of cases. Other scenarios have a low probability of success. Conclusions: The control of the outbreak in Peru during pre-quarantine stage demanded requirements that were difficult to comply with, therefore quarantine was necessary; to successfully suspend it would require a significant reduction in the spread of the disease, early isolation of positives and follow-up of all contacts of positive patients. © 2020, Instituto Nacional de Salud. All rights reserved.
AB - Objectives: To determine the probability of controlling the outbreak of COVID-19 in Peru, in a pre- and post-quarantine scenario using mathematical simulation models. Materials and methods: Outbreak simulations for the COVID-19 pandemic are performed, using stochastic equations under the following assumptions: a pre-quarantine population R0 of 2.7 or 3.5, a post-quarantine R0 of 1.5, 2 or 2.7, 18% or 40%, of asymptomatic positives and a maximum response capacity of 50 or 150 patients in the intensive care units. The success of isolation and contact tracing is evaluated, no other mitigation measures are included. Results: In the pre-quarantine stage, success in controlling more than 80% of the simulations occurred only if the isolation of positive cases was implemented from the first case, after which there was less than 40% probability of success. In post-quarantine, with 60 positive cases it is necessary to isolate them early, track all of their contacts and decrease the R0 to 1.5 for outbreak control to be successful in more than 80% of cases. Other scenarios have a low probability of success. Conclusions: The control of the outbreak in Peru during pre-quarantine stage demanded requirements that were difficult to comply with, therefore quarantine was necessary; to successfully suspend it would require a significant reduction in the spread of the disease, early isolation of positives and follow-up of all contacts of positive patients. © 2020, Instituto Nacional de Salud. All rights reserved.
KW - Infección por Coronavirus; Brotes; Vigilancia; Modelación de Decisiones (fuente: DeCS BIREME).
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-85088968627&partnerID=MN8TOARS
U2 - 10.17843/RPMESP.2020.372.5405
DO - 10.17843/RPMESP.2020.372.5405
M3 - Artículo (Contribución a Revista)
VL - 37
SP - 195
EP - 202
JO - Revista Peruana de Medicina Experimental y Salud Publica
JF - Revista Peruana de Medicina Experimental y Salud Publica
IS - 2
ER -