STD NMR spectroscopy: A case study of fosfomycin binding interactions in living bacterial cells

Cíntia D.F. Milagre; Luís Fernando Cabeça; Lucas G. Martins; Anita J. Marsaioli

doi:10.1590/S0103-50532011000200014

STD NMR spectroscopy: A case study of fosfomycin binding interactions in living bacterial cells

Cíntia D.F. Milagre
, Luís Fernando Cabeça
, Lucas G. Martins
, Anita J. Marsaioli

Research output: Contribution to journal › Article (Contribution to Journal) › peer-review

5 Scopus citations

Abstract

A saturation transfer difference (STD) NMR experiment was successfully employed to observe the binding interactions of fosfomycin resistant and non-resistant bacterial strains using living cell suspensions, without the need for isotopic labelling of the ligand or receptor.

Original language	English
Pages (from-to)	286-291
Number of pages	6
Journal	Journal of the Brazilian Chemical Society
Volume	22
Issue number	2
DOIs	https://doi.org/10.1590/S0103-50532011000200014
State	Published - 2011
Externally published	Yes

Keywords

Fosfomycin
Ligand-target interactions
Liposomes
Membrane-bound proteins
STD NMR in living bacterial cells

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10.1590/S0103-50532011000200014

Cite this

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title = "STD NMR spectroscopy: A case study of fosfomycin binding interactions in living bacterial cells",

abstract = "A saturation transfer difference (STD) NMR experiment was successfully employed to observe the binding interactions of fosfomycin resistant and non-resistant bacterial strains using living cell suspensions, without the need for isotopic labelling of the ligand or receptor.",

keywords = "Fosfomycin, Ligand-target interactions, Liposomes, Membrane-bound proteins, STD NMR in living bacterial cells",

author = "Milagre, \{C{\'i}ntia D.F.\} and Cabe{\c c}a, \{Lu{\'i}s Fernando\} and Martins, \{Lucas G.\} and Marsaioli, \{Anita J.\}",

year = "2011",

doi = "10.1590/S0103-50532011000200014",

language = "Ingl{\'e}s",

volume = "22",

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journal = "Journal of the Brazilian Chemical Society",

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publisher = "Sociedade Brasileira de Quimica",

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T1 - STD NMR spectroscopy

T2 - A case study of fosfomycin binding interactions in living bacterial cells

AU - Milagre, Cíntia D.F.

AU - Cabeça, Luís Fernando

AU - Martins, Lucas G.

AU - Marsaioli, Anita J.

PY - 2011

Y1 - 2011

N2 - A saturation transfer difference (STD) NMR experiment was successfully employed to observe the binding interactions of fosfomycin resistant and non-resistant bacterial strains using living cell suspensions, without the need for isotopic labelling of the ligand or receptor.

AB - A saturation transfer difference (STD) NMR experiment was successfully employed to observe the binding interactions of fosfomycin resistant and non-resistant bacterial strains using living cell suspensions, without the need for isotopic labelling of the ligand or receptor.

KW - Fosfomycin

KW - Ligand-target interactions

KW - Liposomes

KW - Membrane-bound proteins

KW - STD NMR in living bacterial cells

UR - https://www.scopus.com/pages/publications/79751506497

U2 - 10.1590/S0103-50532011000200014

DO - 10.1590/S0103-50532011000200014

M3 - Artículo (Contribución a Revista)

AN - SCOPUS:79751506497

SN - 0103-5053

VL - 22

SP - 286

EP - 291

JO - Journal of the Brazilian Chemical Society

JF - Journal of the Brazilian Chemical Society

IS - 2

ER -

STD NMR spectroscopy: A case study of fosfomycin binding interactions in living bacterial cells

Abstract

Keywords

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