TY - JOUR
T1 - Mapping of somatostatin-28 (1-12) in the alpaca (Lama pacos) brainstem
AU - De Souza, Eliana
AU - Sánchez, Manuel Lisardo
AU - Aguilar, Luís Ángel
AU - Díaz-Cabiale, Zaida
AU - Narváez, José Ángel
AU - Coveñas, Rafael
N1 - Publisher Copyright:
© 2015 Wiley Periodicals, Inc.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - Using an indirect immunoperoxidase technique, we studied the distribution of cell bodies and fibers containing somatostatin-28 (1-12) in the alpaca brainstem. Immunoreactive fibers were widely distributed throughout the whole brainstem: 34 brainstem nuclei/regions showed a high or a moderate density of these fibers. Perikarya containing the peptide were widely distributed throughout the mesencephalon, pons and medulla oblongata. Cell bodies containing somatostatin-28 (1-12) were observed in the lateral and medial divisions of the marginal nucleus of the brachium conjunctivum, reticular formation (mesencephalon, pons and medulla oblongata), inferior colliculus, periaqueductal gray, superior colliculus, pericentral division of the dorsal tegmental nucleus, interpeduncular nucleus, nucleus of the trapezoid body, vestibular nucleus, motor dorsal nucleus of the vagus, nucleus of the solitary tract, nucleus praepositus hypoglossi, and in the substantia nigra. This widespread distribution indicates that somatostatin-28 (1-12) is involved in multiple physiological actions in the alpaca brainstem.
AB - Using an indirect immunoperoxidase technique, we studied the distribution of cell bodies and fibers containing somatostatin-28 (1-12) in the alpaca brainstem. Immunoreactive fibers were widely distributed throughout the whole brainstem: 34 brainstem nuclei/regions showed a high or a moderate density of these fibers. Perikarya containing the peptide were widely distributed throughout the mesencephalon, pons and medulla oblongata. Cell bodies containing somatostatin-28 (1-12) were observed in the lateral and medial divisions of the marginal nucleus of the brachium conjunctivum, reticular formation (mesencephalon, pons and medulla oblongata), inferior colliculus, periaqueductal gray, superior colliculus, pericentral division of the dorsal tegmental nucleus, interpeduncular nucleus, nucleus of the trapezoid body, vestibular nucleus, motor dorsal nucleus of the vagus, nucleus of the solitary tract, nucleus praepositus hypoglossi, and in the substantia nigra. This widespread distribution indicates that somatostatin-28 (1-12) is involved in multiple physiological actions in the alpaca brainstem.
KW - Camelids
KW - Immunocytochemistry
KW - Medulla oblongata
KW - Mesencephalon
KW - Pons
UR - http://www.scopus.com/inward/record.url?scp=84928209067&partnerID=8YFLogxK
U2 - 10.1002/jemt.22482
DO - 10.1002/jemt.22482
M3 - Artículo (Contribución a Revista)
C2 - 25754727
AN - SCOPUS:84928209067
SN - 1059-910X
VL - 78
SP - 363
EP - 374
JO - Microscopy Research and Technique
JF - Microscopy Research and Technique
IS - 5
ER -